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[Expert Solution]: A nurse is caring for a patient (a…

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A nurse is caring for a patient (a documented overproducer of uric acid) who was recently prescribed lesinurad 200 mg PO daily for management of gout. In addition to lesinurad, the patient is also receiving colchicine for gout and amlodipine for hypertension. Which rationale explains why the nurse would call the health care provider before administering lesinurad? Lesinurad interacts with colchicine, and they cannot be given together. Lesinurad must be administered with allopurinol or febuxostat. Lesinurad may worsen this patient’s hypertension, even when receiving antihypertensive therapy. Lesinurad should not be given to patients who are documented overproducers of uric acid because it is not effective.

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