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[Answered]: A patient with advanced prostate cancer will…

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A patient with advanced prostate cancer will begin treatment with leuprolide [Lupron]. The provider has ordered flutamide to be given as adjunct therapy. The patient asks the healthcare provider why both drugs are necessary. The healthcare provider will tell the patient that: flutamide reduces the side effects, such as hot flushes, caused by leuprolide. flutamide suppresses initial tumor flare caused leuprolide. the combination of both drugs increases cancer survival. leuprolide helps to reduce the toxicity of flutamide.

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